Haematology team
| Dr E O’Donovan Consultant Haematologist |
x2198 |
| Dr P Kaczmarek Consultant Haematologist |
x6474 |
| Dr B Jackson Consultant Haematologist |
x1692 |
| Dr G Ivanov Consultant Haematologist |
x6472 |
| Haematology Clinic Appointments |
East Surrey Hospital x 6473 Crawley Hospital x 3070 |
Validity of results
Quality assurance programmes are in operation to ensure a high degree of accuracy and precision of all tests. However, if you doubt the validity of a result please let us know at once. Most samples are kept for 2—3 days and during this time it is usually possible to check any result.
Turnaround times
The department prioritises all work received from A&E, ITU, SCBU and other critical care units, together with any other emergency samples. The department aims to ensure the results of the investigations for the immediate management of the patient will be available on the pathology computer system within 1 hour of receiving the samples.
All other inpatient samples together with GP and out-patient work identified as urgent are prioritised. The department aims to ensure the routine investigations will be available on the pathology computer system within 2 hours of receiving the samples.
Samples received from GP surgeries and out-patient clinics samples will be processed on the day of receipt. All authorised surgery results are transmitted via the GP links at regular intervals. Please indicate a telephone number on the request form in order that the laboratory may phone a result out of hours if required.
| Tests | Specimen bottle | Min vol | Results available | Comments | Reference ranges |
|
APTT |
Blue Topped citrate Vacuette |
3.5ml |
See Turnaround Times |
Accurate filling of specimen bottle is essential to obtain a valid result. Coagulation samples must be processed on the day the sample is taken, preferably within 4 hours. |
Adult range |
|
BLEEDING TIME |
Please contact the Consultant Haematologist to arrange. The patient must not have taken aspirin for one week beforehand |
Interpretation will be quoted with the result. |
|||
|
CHROMOSOME STUDIES |
Green topped lithium heparin |
6ml |
2 weeks |
Samples are referred to St Georges. Special arrangement with laboratory is necessary. |
n/a |
|
CLOTTING SCREEN |
Blue Topped citrate Vacuette |
3.5ml |
See Turnaround Times |
Screen comprises PT and APTT. See APTT |
Refer to APTT, PT,INR |
|
FIBRINOGEN |
Blue Topped citrate Vacuette |
3.5ml |
See Turnaround Times |
Accurate filling of specimen bottle is essential to obtain a valid result. Coagulation samples must be processed on the day the sample is taken, preferably within 4 hours. |
1.8-4.0g/L |
|
FACTOR ASSAYS |
Blue Topped citrate Vacuette |
2x3.5ml |
2-3 Weeks |
Accurate filling of specimen bottle is essential to obtain a valid result. Coagulation samples must be processed on the day the sample is taken, preferably within 4 hours. |
50-150 u/dL |
|
AT III |
Blue Topped citrate Vacuette |
3.5ml |
2-3 Weeks |
Accurate filling of specimen bottle is essential to obtain a valid result. Coagulation samples must be processed on the day the sample is taken, preferably within 4 hours. |
82/128 u/dL |
|
Protein C |
Blue Topped citrate Vacuette |
3.5ml |
2-3 Weeks |
Accurate filling of specimen bottle is essential to obtain a valid result. Coagulation samples must be processed on the day the sample is taken, preferably within 4 hours. |
70-140 u/dL |
|
Protein S(free Ag) |
Blue Topped citrate Vacuette |
3.5ml |
2-3 Weeks |
Accurate filling of specimen bottle is essential to obtain a valid result. Coagulation samples must be processed on the day the sample is taken, preferably within 4 hours. |
54.7-123.7 u/dL |
|
APCR (Modified) |
Blue Topped citrate Vacuette |
3.5ml |
2-3 Weeks |
Accurate filling of specimen bottle is essential to obtain a valid result. Coagulation samples must be processed on the day the sample is taken, preferably within 4 hours. |
2.61-3.32 ratio |
|
LUPUS TESTS |
Blue Topped citrate Vacuette |
2 x 3.5ml |
2-3 weeks |
Accurate filling of specimen bottle is essential to obtain a valid result. Coagulation samples must be processed on the day the sample is taken, preferably within 4 hours. |
|
|
D-DIMER |
Blue Topped citrate Vacuette |
3.5ml |
See Turnaround Times |
A specific fibrin degradation product. Levels found in DIC, DVT/PE, thrombolytic therapy. |
<230 ng/ml as a negative predictor in DVT/PE. |
|
DIRECT COOMBS TEST |
Purple topped EDTA |
2ml |
See Turnaround Times |
Suggest discuss with Consultant Haematologist. |
Reported as POS/NEG |
|
ESR |
Mauve topped long tube (citrate) monovette |
3.5ml |
See Turnaround Times |
Should be processed on the day of venesection |
Adult range |
|
FULL BLOOD COUNT |
Purple topped EDTA |
2ml |
See Turnaround Times |
Age dependent, parameters refer to individual report for range. |
|
|
G-6-P-DEHYDROGENASE |
Purple topped EDTA |
2ml |
3 days |
Quantitation studies performed at reference centre. |
Screening test reported as normal or deficient. |
|
Hb A2 |
Purple topped EDTA |
2ml |
3 days |
||
|
Hb electrophoresis |
Purple topped EDTA |
2ml |
1 week |
Full interpretive comments on the report. |
|
|
INR |
Blue topped citrate |
3.5ml |
See Turnaround Times |
A derived value from the prothrombin time for patients taking warfarin. Coagulation samples must be processed on the day the sample is taken. |
Therapeutic ranges for patients on oral anticoagulants. |
|
MALARIA PARASITES |
Purple topped EDTA |
2ml |
See Turnaround Times |
Repeated examinations of blood film may be necessary if parasites not identified and there is clinical suspicion of infection. Positive results are confirmed with Malaria Reference Laboratory. Please indicate pertinent travel history and anti-malarial prophylaxis. |
Reported as POS/NEG. |
|
MONOSPOT |
Purple topped EDTA |
2ml |
See Turnaround Times |
Test may remain positive for many months after initial episode of infectious mononuclieosis. Further confirmatory tests of infection should be discussed with Consultant Haematologist or Consultant Microbiologist. |
Reported as POS/NEG |
|
PROTHROMBIN TIME (PT) |
Purple topped EDTA |
3.5ml |
See Turnaround Times |
Accurate filling of specimen bottle is essential to obtain a valid result. Coagulation samples must be processed on the day the sample is taken, preferably within 4 hours. |
Adult reference range9.5 - 12.0 secs. |
|
PYRUVATE KINASE |
Purple topped EDTA |
2ml |
3 days |
Screening test for the deficiency, which is autosomally inherited. Quantitation studies performed at reference centre. |
Screening test reported as normal or deficient. |
|
RETICULOCYTES |
Purple topped EDTA |
2ml |
See Turnaround Times |
Reticulocytes reflect the rate of red cell production. In states of bleeding, haemolysis, and recovery from marrow suppression. The EDTA sample must be processed on the day of venesection |
Adult range |
Addresses of referral laboratories for chemical pathology and haematology
|
ANTENATAL SCREENING SERVICE ENVIRONMENTAL MEDICINE DEPT. ST BARTHOLOMEWS HOSPITAL CHARTERHOUSE SQUARE LONDON EC1M 6BQ |
BIOCHEMISTRY DEPT. EPSOM HOSPITAL LABORATORIES WEST PARK HOSPITAL HORTON LANEEPSOM, SURREY, KT19 8PB Tel. 01372 734724 |
|
CHEMICAL PATHOLOGY DEPT. HOSPITAL FOR SICK CHILDREN GREAT ORMOND STREET LONDON WC15 3JH Tel 0207 405 9200 |
DEPT. OF CLINICAL CHEMISTRY 5TH FLOOR TOWER BLOCK GUY’S HOSPITAL ST THOMAS STREET LONDON SE1 9RT |
|
CHEMICAL PATHOLOGY 2nd FLOOR, JENNER WING ST GEORGE’S HOSPITAL TOOTING LONDON SW17 0RE |
CHEMICAL PATHOLOGY MAYDAY UNIVERSITY HOSPITAL MAYDAY ROAD THORNTON HEATH SURREY CR7 7YE |
|
CHEMISTRY DEPARTMENT PATHOLOGY LABORATORY ST HELIER HOSPITAL WRYTHE LANE CARSHALTON SURREY SM2 1AA Tel. 0208 296 3160 |
CLINICAL LABORATORY ROYAL SURREY COUNTY HOSPITAL EGERTON ROAD GUILDFORD SURREY GU2 5XX Tel 01483 464121 |
|
CLINICAL PATHOLOGY MIDDLESEX HOSPITAL CLEVELAND STREET LONDON W1P 6DB |
Dept of Clinical Biochemistry CITY HOSPITAL NHS TRUST Dudley Road Birmingham, West Midlands B18 7QH |
|
DR WYN GRIFFITHS CLINICAL BIOCHEMISTRY LEWISHAM HOSPITAL LONDON SE13 6LH |
HAREFIELD HOSPITAL HILL END ROAD HAREFIELD MIDDLESEX UB9 6JH |
|
KINGS COLLEGE HOSPITAL INSTITUTE OF LIVER STUDIES DENMARK HILL LONDON SE5 9RS |
MICROBIOLOGY DEPARTMENT ROYAL BROMPTON HOSPITAL SYDNEY STREET LONDON SW3 6NP |
|
PRINCESS ROYAL HOSPITAL LEWES ROAD HAYWARDS HEATH W SUSSEX RH16 4EX |
Enzyme Laboratory Institute of Child Health 30 Guildford Street LONDON WC1N 1EH |
|
PROTEIN REFERENCE UNIT DEPT OF IMMUNOLOGY P.O. BOX 894 SHEFFIELD S5 7YT Tel. 0114 571 5552 |
REGIONAL ENDOCRINE LABORATORY SELLY OAK HOSPITAL RADDLEBARN ROAD BIRMINGHAM B29 6JD Tel 0121 627 1627 ext 52304 |
|
St George’s Hospital Department of Chemical Pathology Level 2 Jenner Wing Blackshaw Road Tooting SW17 0QT |
SAS RECEPTION PATHOLOGY CENTRE, AREA GHAMMERSMITH HOSPITAL DUCANE ROAD LONDON W12 OHS Tel. 0208 740 3032 |
|
THE POISONS UNIT NEW CROSS HOSPITAL AVONLEY ROAD LONDON SE14 5ER |
TRACE ELEMENTS LABORATORY CENTRE FOR CLINICAL SCIENCE & MEASUREMENT UNIVERSITY OF SURREY GUILDFORD GU2 5XH Tel. 01483 879978 |
|
UNIVERSITY COLLEGE LONDON HOSPITAL DEPT OF CLINICAL BIOCHEMISTRY 3rd FLOOR 60 WHITFIELD STREET LONDON W1T 4EU Tel. 0845 155 5000 Ext 2955 |
DR M.N. BADMINTON THE PORPHYRIA SERVICEDEPT.OF MEDICAL BIOCHEMISTRY AND IMMUNOLOGY UNIVERSITY HOSPITAL OF WALES HEATH PARK CARDIFF CF14 4XW |
|
MRD Group Leukaemia Research Laboratory Department of Haematology Hammersmith Hospital Du Cane Road London W12 0NN |
CLINICAL NEUROCHEMISTRY DEPT ROOM 901 QUEENS SQUARE HOUSE THE NATIONAL HOSPITAL QUEENS SQUARE LONDON WC1N 3BG Tel. 0207 771 4361 |
|
Department of Haematology St George’s Medical School Blackshaw Way London SW17 0RE |
ROYAL MARSDEN HOSPITALSection of haemato-oncologyBrookes lawley buildingCotswold roadSuttonSurrey SM2 5NGPhone: 020 8722 4221 |
|
Haemophilia Centre St. Thomas Hospital Lambeth Palace Road London SE1 7EH |
Protein Laboratory Department of Haematology King’s Healthcare NHS Trust King’s College Hospital Denmark Hill London SE59 RS |
|
PHLS Malaria Reference Laboratory London School of Hygiene and Tropical Medicine Keppel (Gower) Street London WC1E 7HT |
Royal Sussex Hospital Virology Department Brighton |